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KMID : 0365919930290100027
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Journal of the Pusan Medical Association
1993 Volume.29 No. 10 p.27 ~ p.33
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Hemodynamic Changes after Induction of Anesthesia with Propofol or Thiopental
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유재민
권재영/백승완/김인세/정규섭
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Abstract
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Forty ASA I, II patients received either propofol 2.2 mg/kg or thiopental 4 mg/kg for induction of general inhalational anesthesia together with 2% enflurane with 50% N2O and neuromuscular blocking agents. Hemodynamic changes during induction and
trcheal intubation are as follows.
1. The systolic and diastolic arterial pressures were more reduced In propofol induction than thiopental induction.
2. With thiopental, the heart rates were increased after induction and tracheal int ubation, but with propofol, the heart rates were not increased after tracheal intubation.
3. The cardiac outputs were decreased after thiopental induction. But maintained after propofol induction.
4. The systemic vascular resistances were decreased after propofol induction.
From the above results, we suggest that propofol is relatively comfortable drug during induction of general inhalational anesthesia without significant hemodynamic changes except decreasing systemic vascular resistance.
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